Onycholysis is the term for nails separating from the nail bed. This can be caused by medications or harsh chemicals, but sometimes it signals thyroid problems. The condition usually starts at the tip of the nail and moves toward the cuticle, creating an opaque or white area due to air under the nail. Other causes include psoriasis, fungal infections, trauma, and certain medications, especially tetracycline antibiotics. Frequent manicures or prolonged exposure to water can make the condition worse. Treatment depends on the cause but often involves keeping the affected nails dry and clean, avoiding activities that worsen the separation, and allowing the nail to grow out naturally. For cases related to systemic diseases like thyroid problems, treating the underlying condition is key to preventing recurrence.
